| Cover Picture: Classification of Organic Molecules by Molecular Quantum Numbers (ChemMedChem 11/2009) Kong T. Nguyen, Lorenz C. Blum, Ruud van Deursen, Jean-Louis Reymond 1765  |
| Full: PDF (961 K) |
| Inside Cover: From Structure-Activity to Structure-Selectivity Relationships: Quantitative Assessment, Selectivity Cliffs, and Key Compounds (ChemMedChem 11/2009) Lisa Peltason, Ye Hu, Jürgen Bajorath 1766  |
| Full: PDF (438 K) |
| Graphical Abstract: ChemMedChem 11/2009 1767-1774 |
| Full: PDF (1149 K) |
| Spotlights on our sister journals: ChemMedChem 11/2009 1776-1778 |
| Full: PDF (866 K) |
| Aryloxy Phosphoramidate Triesters: a Technology for Delivering Monophosphorylated Nucleosides and Sugars into Cells Youcef Mehellou, Jan Balzarini, Christopher McGuigan 1779-1791  |
| Full: PDF (426 K) |
| Chemical and Structural Biology to Direct the Repurposing of Sulindac Jeffrey R. Simard, Daniel Rauh 1793-1795  |
| Full: PDF (332 K) |
| Synthesis and Pharmacological Characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, Silicon Analogues of the RARα-Selective Retinoid Agonists AM80 (Tamibarotene) and AM580 Reinhold Tacke, Volker Müller, Matthias W. Büttner, W. Peter Lippert, Rüdiger Bertermann, Jürgen O. Daiß, Harshal Khanwalkar, Audrey Furst, Claudine Gaudon, Hinrich Gronemeyer 1797-1802  |
| Full: PDF (416 K) |
| Classification of Organic Molecules by Molecular Quantum Numbers Kong T. Nguyen, Lorenz C. Blum, Ruud van Deursen, Jean-Louis Reymond 1803-1805  |
| Full: PDF (480 K) |
| Identification and Validation of a Potent Type II Inhibitor of Inactive Polo-like Kinase 1 Sarah Keppner, Ewgenij Proschak, Gisbert Schneider, Birgit Spänkuch 1806-1809  |
| Full: PDF (408 K) |
| The Roles of 3′ and 4′ Hydroxy Groups in α-Galactosylceramide Stimulation of Invariant Natural Killer T Cells Chengfeng Xia, Wenpeng Zhang, Yalong Zhang, Wenlan Chen, Janos Nadas, Ryan Severin, Robert Woodward, Bin Wang, Xin Wang, Mitchell Kronenberg, Peng G. Wang 1810-1815  |
| Full: PDF (252 K) |
| High-Speed Microwave-Assisted Synthesis of the Trifluoromethylpyrazol-Derived Canonical Transient Receptor Potential (TRPC) Channel Inhibitor Pyr3 Toma N. Glasnov, Klaus Groschner, C. Oliver Kappe 1816-1818  |
| Full: PDF (188 K) |
| Synthesis and Evaluation of Imidazo[2,1-b]thiazoles as Iodide Efflux Inhibitors in Thyrocytes Nathalie Lecat-Guillet, Yves Ambroise 1819-1830  |
| Full: PDF (432 K) |
| 3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and Related Diethyl Esters: Potent Cytotoxins with Multi-Drug-Resistance Reverting Properties Swagatika Das, Umashankar Das, Ponniah Selvakumar, Rajendra K. Sharma, Jan Balzarini, Erik De Clercq, Joseph Molnár, Julianna Serly, Zoltán Baráth, Gabriele Schatte, Brian Bandy, Dennis K. J. Gorecki, Jonathan R. Dimmock 1831-1840  |
| Full: PDF (302 K) |
| Studies on the Synthesis and Activity of Three Tripalladium Complexes Containing Planaramine Ligands Mohammad Farhad, Jun Qing Yu, Philip Beale, Keith Fisher, Fazlul Huq 1841-1849  |
| Full: PDF (346 K) |
| Synthesis of Modified 4H-1,2,4-Benzothiadiazine-1,1-dioxides and Determination of their Affinity and Selectivity for Different Types of KATP Channels Stefan Lachenicht, Andreas Fischer, Claas Schmidt, Marcus Winkler, Achim Rood, Horst Lemoine, Manfred Braun 1850-1858  |
| Full: PDF (320 K) |
| Molecular Fingerprint Recombination: Generating Hybrid Fingerprints for Similarity Searching from Different Fingerprint Types Britta Nisius, Jürgen Bajorath 1859-1863  |
| Full: PDF (455 K) |
| From Structure-Activity to Structure-Selectivity Relationships: Quantitative Assessment, Selectivity Cliffs, and Key Compounds Lisa Peltason, Ye Hu, Jürgen Bajorath 1864-1873  |
| Full: PDF (980 K) |
| Structural Model for the Binding Sites of Allosterically Potentiating Ligands on Nicotinic Acetylcholine Receptors Edgar Luttmann, Jürgen Ludwig, Anja Höffle-Maas, Marek Samochocki, Alfred Maelicke, Gregor Fels 1874-1882  |
| Full: PDF (1576 K) |
| Combined Pharmacophore Modeling, Docking, and 3D QSAR Studies of ABCB1 and ABCC1 Transporter Inhibitors Ilza K. Pajeva, Christoph Globisch, Michael Wiese 1883-1896  |
| Full: PDF (788 K) |
| Activators of P-glycoprotein: Structure-Activity Relationships and Investigation of their Mode of Action Katja Sterz, Lars Möllmann, Anna Jacobs, Dieter Baumert, Michael Wiese 1897-1911  |
| Full: PDF (431 K) |
| Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents Abdallah Hamze, Anne Giraud, Samir Messaoudi, Olivier Provot, Jean-François Peyrat, Jérôme Bignon, Jian-Miao Liu, Joanna Wdzieczak-Bakala, Sylviane Thoret, Joëlle Dubois, Jean-Daniel Brion, Mouad Alami 1912-1924  |
| Full: PDF (823 K) |
| 4,4-Dimethyl- and Diastereomeric 4-Hydroxy-4-methyl- (2S)-Glutamate Analogues Display Distinct Pharmacological Profiles at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters Lennart Bunch, Darryl S. Pickering, Thierry Gefflaut, Virginie Vinatier, Virgil Helaine, Ahmad Amir, Birgitte Nielsen, Anders A. Jensen 1925-1929  |
| Full: PDF (308 K) |
| Synthesis and Biological Evaluation of Chromium Bioorganometallics Based on the Antibiotic Platensimycin Lead Structure Malay Patra, Gilles Gasser, Antonio Pinto, Klaus Merz, Ingo Ott, Julia E. Bandow, Nils Metzler-Nolte 1930-1938  |
| Full: PDF (422 K) |
| 2-Acylaminopyridin-4-ylimidazoles as p38 MAP Kinase Inhibitors: Design, Synthesis, and Biological and Metabolic Evaluations Katharina Ziegler, Dominik R. J. Hauser, Anke Unger, Wolfgang Albrecht, Stefan A. Laufer 1939-1948  |
| Full: PDF (377 K) |
| The Cannabinoid Receptors. Edited by Patricia H. Reggio. David Selwood 1949 |
| Full: PDF (89 K) |
| Cancer Proteomics: From Bench to Bedside. Edited by Sayed S. Daoud. Laszlo Prokai 1950-1951 |
| Full: PDF (90 K) |
| Preview: ChemMedChem 12/2009 1955 |
| Full: PDF (95 K) |