Journal of Medicinal Chemistry
Volume 41, Issue 22 (October 22, 1998)
Copyright © 1998
American Chemical Society
| COMMUNICATIONS TO THE EDITOR | |
4181-4185 | Synthesis and Modeling Studies of a Potent Conformationally Rigid Muscarinic Agonist: 1-Azabicyclo[2.2.1]heptanespirofuranone
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4186-4189 | Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone for Potential Use against Alzheimer's Disease
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4190-4195 | Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor
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4196-4198 | 6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2,3-b]pyridine (RWJ 68354): A Potent and Selective p38 Kinase Inhibitor
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EXPEDITED ARTICLES | |
4199-4206 | Synthesis and Evaluation of N-[11C]Methylated Analogues of Epibatidine as Tracers for Positron Emission Tomographic Studies of Nicotinic Acetylcholine Receptors
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ARTICLES | |
4207-4215 | Derivation of a Pharmacophore Model for Anandamide Using Constrained Conformational Searching and Comparative Molecular Field Analysis
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4216-4223 | Novel Cyclic Compounds as Potent Phosphodiesterase 4 Inhibitors
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4224-4231 | In Vitro and in Vivo Activities of Oligodeoxynucleotide-Based Thrombin Inhibitors Containing Neutral Formacetal Linkages
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4232-4239 | Axially Chiral N-Benzyl-N,7-dimethyl-5-phenyl-1,7-naphthyridine-6-carboxamide Derivatives as Tachykinin NK1 Receptor Antagonists: Determination of the Absolute Stereochemical Requirements
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4240-4250 | Design of Benzamidine-Type Inhibitors of Factor Xa
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4251-4260 | Metabolites of the Angiotensin II Antagonist Tasosartan: The Importance of a Second Acidic Group
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4261-4272 | Quantitative Structure-Activity Relationships of 2,4-Diamino-5-(2-X-benzyl)pyrimidines versus Bacterial and Avian Dihydrofolate Reductase
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4273-4278 | Design of New Topoisomerase II Inhibitors Based upon a Quinobenzoxazine Self-Assembly Model
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4279-4287 | Studies on Selectin Blockers. 7. Structure-Activity Relationships of Sialyl Lewis X Mimetics Based on Modified Ser-Glu Dipeptides
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4288-4300 | Potent and Selective Non-Cysteine-Containing Inhibitors of Protein Farnesyltransferase
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4301-4308 | Synthesis of Peptide Aldehyde Derivatives as Selective Inhibitors of Human Cathepsin L and Their Inhibitory Effect on Bone Resorption
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4309-4316 | Novel Calcium Antagonists with Both Calcium Overload Inhibition and Antioxidant Activity. 1. 2-(3,5-Di-tert-butyl-4-hydroxyphenyl)-3-(aminopropyl)thiazolidinones
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4317-4328 | Bis-Cationic Heteroaromatics as Macrofilaricides: Synthesis of Bis-Amidine and Bis-Guanylhydrazone Derivatives of Substituted Imidazo[1,2-a]pyridines
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4329-4342 | Design of Peptidomimetics That Inhibit the Association of Phosphatidylinositol 3-Kinase with Platelet-Derived Growth Factor- Receptor and Possess Cellular Activity
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4343-4353 | 5-Substituted Pyrimidines with a 1,5-Anhydro-2,3-dideoxy-D-arabino-hexitol Moiety at N-1: Synthesis, Antiviral Activity, Conformational Analysis, and Interaction with Viral Thymidine Kinase
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4354-4359 | 5-Benzylidene 1,2-Dihydrochromeno[3,4-f]quinolines, A Novel Class of Nonsteroidal Human Progesterone Receptor Agonists
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4360-4364 | Bisquinolines. 2. Antimalarial N,N-Bis(7-chloroquinolin-4-yl)heteroalkanediamines
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4365-4377 | Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8H-pyrido[2,3-d]pyrimidines: Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors
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4378-4384 | Muscarinic Agonists with Antipsychotic-like Activity: Structure-Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity
 ger Rasmussen,gersen, |
4385-4399 | CoMFA-Based Prediction of Agonist Affinities at Recombinant D1 vs D2 Dopamine Receptors
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4400-4407 | Potent Cyano and Carboxamido Side-Chain Analogues of 1',1'-Dimethyl- 8-Tetrahydrocannabinol
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4408-4420 | Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. 3. Discovery of a Novel Series of N-Alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with Weak Toxicological Effects on Adrenal Glands
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NOTES | |
4421-4423 | Bisphenols That Stimulate Cells To Release Alkali Metal Cations: A Structure-Activity Study
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BOOK REVIEWS | |
4424-4424 | Second Supplements to the Second Edition of Rodd's Chemistry of Carbon Compounds. Volume IV: Heterocyclic Compounds. Part C: Five-Membered Heterocyclic Compounds with Two Hetero-Atoms in the Ring from Groups V and VI of the Periodic Table; Part D: Five-Membered Heterocyclic Compounds with More Than Two Hetero-Atoms in the Ring Edited by M. Sainsbury. Elsevier, Amsterdam. 1998. xvi + 281 pp. 15.5 × 23 cm. ISBN-0-444-828702. $187.00.
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4424-4425 | A Practical Guide to Combinatorial Chemistry Edited by A. W. Czarnik and S. H. DeWitt. American Chemical Society, Washington, D.C. 1997. xiv + 450 pp. 15.5 × 23.5 cm. ISBN 0-8412-3485. $89.95.
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4425-4425 | Analytical Chemistry Edited by R. Kellner, J.-M. Mermet, M. Otto, and H. M. Widmer. Wiley-VCH, New York. 1998. xxv + 916 pp. 21.5 × 30 cm. ISBN 3-527-286101. $84.95.
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4425-4426 | High-Performance Capillary Electrophoresis Edited by Morteza G. Kahaledi. John Wiley & Sons, New York, NY. 1998. xxxii + 1047 pp. 16 × 24 cm. ISBN 0-471-148512. $150.00.
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4426-4426 | The Combinatorial Index By Barry A. Bunin. Academic Press, New York, NY. 1998. xvii + 322 pp. 18 × 26 cm. ISBN 0-12-141340-3. $79.95.
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4426-4427 | Practical Application of Computer-Aided Drug Design Edited by Paul S. Charifson. Marcel Dekker, Inc., New York, NY. 1997. x + 52 pp. 16 × 23.5 cm. ISBN 0-8247-9885-6. $150.00.
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4427-4428 | The Laboratory Companion: A Practical Guide to Materials, Equipment, and Technique By Gary S. Coyne. John Wiley & Sons, New York. 1997. xviii + 527 pp. 18 × 26 cm. ISBN 0-4711-8422-5. $59.95.
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4428-4428 | Emerging Drugs. The Prospect for Improved Medicines. Annual Executive Briefing. Volume 3. Edited by W. C. Bowman, J. D. Fitzgerald, and J. B. Taylor. Ashley Publications Ltd., London. 1998. vi + 397 pp. 21 x 29.54 cm. ISSN 1361-9195. $690.00.
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