1935-1937
| 11-Ketotigogenin Cellobioside (Pamaqueside): A Potent Cholesterol Absorption Inhibitor in the Hamster
Peter A. McCarthy,
Michael P. DeNinno,
Lee A. Morehouse,
Charles E. Chandler,
Faan Wen Bangerter,
Theresa C. Wilson,
Frank J. Urban,
Stanley W. Walinsky,
Patricia G. Cosgrove,
Kimberly Duplantier,
John B. Etienne,
Michael A. Fowler,
John F. Lambert,
John P. O'Donnell,
Susan L. Pezzullo,
Harry A. Watson, Jr.,
Robert W. Wilkins,
Lawrence M. Zaccaro, and
Michael P. Zawistoski
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1938-1940
| Drug Delivery Systems. 2. Camptothecin 20-O-Poly(ethylene glycol) Ester Transport Forms
Richard B. Greenwald,
Annapurna Pendri,
Charles Conover,
Carl Gilbert,
Ross Yang, and
Jing Xia
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1941-1942
| 3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D4 Receptor
Janusz J. Kulagowski,
Howard B. Broughton,
Neil R. Curtis,
Ian M. Mawer,
Mark P. Ridgill,
Raymond Baker,
Frances Emms,
Stephen B. Freedman,
Rosemarie Marwood,
Shil Patel,
Smita Patel,
C. Ian Ragan, and
Paul D. Leeson
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1943-1945
| 5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors
Michael Rowley,
Howard B. Broughton,
Ian Collins,
Raymond Baker,
Frances Emms,
Rosemarie Marwood,
Shil Patel,
Smita Patel,
C. Ian Ragan,
Stephen B. Freedman, and
Paul D. Leeson
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1946-1948
| Design and Synthesis of 2-Naphthoate Esters as Selective Dopamine D4 Antagonists
Izzy Boyfield,
Thomas H. Brown,
Martyn C. Coldwell,
David G. Cooper,
Michael S. Hadley,
Jim J. Hagan,
Maureen A. Healy,
Amanda Johns,
Ron J. King,
Derek N. Middlemiss,
David J. Nash,
Graham J. Riley,
Emma E. Scott,
Stephen A. Smith, and
Geoffrey Stemp
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1949-1955
| Screening Derivatized Peptide Libraries for Tight Binding Inhibitors to Carbonic Anhydrase II by Electrospray Ionization-Mass Spectrometry
Jinming Gao,
Xueheng Cheng,
Ruidan Chen,
George B. Sigal,
James E. Bruce,
Brenda L. Schwartz,
Steven A. Hofstadler,
Gordon A. Anderson,
Richard D. Smith, and
George M. Whitesides
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1956-1966
| Asymmetric Syntheses, Opioid Receptor Affinities, and Antinociceptive Effects of 8-Amino-5,9-methanobenzocyclooctenes, a New Class of Structural Analogues of the Morphine Alkaloids
Arthur G. Schultz,,1a
Aihua Wang,1a
Carlos Alva,1a
Alice Sebastian,1a
Stanley D. Glick,1b
Darlene C. Deecher,1b and
Jean M. Bidlack1c
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1967-1974
| (Aminoalkyl)indole Isothiocyanates as Potential Electrophilic Affinity Ligands for the Brain Cannabinoid Receptor
Koichiro Yamada,
Kenner C. Rice,
Judith L. Flippen-Anderson,
Michael A. Eissenstat,
Susan J. Ward,
M. Ross Johnson, and
Allyn C. Howlett
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1975-1980
| Antitumor Agents. 166. Synthesis and Biological Evaluation of 5,6,7,8-Substituted-2-phenylthiochromen-4-ones
Hui-Kang Wang,
Kenneth F. Bastow,
L. Mark Cosentino, and
Kuo-Hsiung Lee
[Full Article -
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1981-1990
| Decomposition Pathways and in Vitro HIV Inhibitory Effects of IsoddA Pronucleotides: Toward a Rational Approach for Intracellular Delivery of Nucleoside 5'-Monophosphates
Gilles Valette,
Alain Pompon,
Jean-Luc Girardet,
Loredana Cappellacci,
Palmarisa Franchetti,
Mario Grifantini,
Paolo La Colla,
Anna Giulia Loi,
Christian Périgaud,
Gilles Gosselin, and
Jean-Louis Imbach
[Full Article -
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1991-2007
| Aminodiol HIV Protease Inhibitors. Synthesis And Structure-Activity Relationships Of P1/P1' Compounds: Correlation between Lipophilicity and Cytotoxicity
Ping Chen,
Peter T. W. Cheng,
Masud Alam,
Barbara D. Beyer,
Gregory S. Bisacchi,
Tamara Dejneka,
Adelaide J. Evans,
Jill A. Greytok,
Mark A. Hermsmeier,
W. Griffith Humphreys,
Glenn A. Jacobs,
Octavian Kocy,
Pin-Fang Lin,
Karen A. Lis,
Michael A. Marella,
Denis E. Ryono,
Amy K. Sheaffer,
Steven H. Spergel,
Chong-qing Sun,
Joseph A. Tino,
Gregory Vite,
Richard J. Colonno,
Robert Zahler, and
Joel C. Barrish
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2008-2017
| Rational Design of True Hirudin Mimetics: Synthesis and Characterization of Multisite-Directed -Thrombin Inhibitors
Angela Lombardi,
Flavia Nastri,
Rossella Della Morte,
Armando Rossi,
Alfredo De Rosa,
Norma Staiano,
Carlo Pedone, and
Vincenzo Pavone
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2018-2029
| Oxidation Chemistry of (-)-Norepinephrine in the Presence of L-Cysteine
Xue-Ming Shen and
Glenn Dryhurst
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2030-2039
| Partially Modified Retro-Inverso Pseudopeptides as Non-natural Ligands for the Human Class I Histocompatibility Molecule HLA-A2
Gilles Guichard,
Francine Connan,
Roland Graff,
Marina Ostankovitch,
Sylviane Muller,
Jean-Gérard Guillet,
Jeannine Choppin, and
Jean-Paul Briand
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2040-2046
| Synthesis of Novel Se-Substituted Selenocysteine Derivatives as Potential Kidney Selective Prodrugs of Biologically Active Selenol Compounds: Evaluation of Kinetics of -Elimination Reactions in Rat Renal Cytosol
Ioanna Andreadou,
Wiro M. P. B. Menge,
Jan N. M. Commandeur,
Eduard A. Worthington, and
Nico P. E. Vermeulen
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2047-2054
| Discovery of Novel, Non-Peptide HIV-1 Protease Inhibitors by Pharmacophore Searching
Shaomeng Wang,
G. W. A. Milne,
Xinjian Yan,
Isadora J. Posey,
Marc C. Nicklaus,
Lisa Graham, and
William G. Rice
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2055-2059
| Studies on Selectin Blockers. 2. Novel Selectin Blocker as Potential Therapeutics for Inflammatory Disorders
Yukihisa Wada,
Tadayuki Saito,
Naomi Matsuda,
Hiroshi Ohmoto,
Kohichiro Yoshino,
Masami Ohashi, and
Hirosato Kondo
, Hideharu Ishida,
Makoto Kiso, and
Akira Hasegawa
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2060-2067
| Inhibitors of Human Immunodeficiency Virus Type 1 Protease Containing 2-Aminobenzyl-Substituted 4-Amino-3-hydroxy-5-phenylpentanoic Acid: Synthesis, Activity, and Oral Bioavailability
Philipp Lehr,
Andreas Billich,
Brigitte Charpiot,
Peter Ettmayer,
Dieter Scholz,
Brigitte Rosenwirth, and
Hubert Gstach
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2068-2080
| Novel Selective and Partial Agonists of 5-HT3 Receptors. Part 1. Synthesis and Biological Evaluation of Piperazinopyrrolothienopyrazines
Sylvain Rault,
Jean-Charles Lancelot,
Hervé Prunier,
Max Robba,
Pierre Renard,
Philippe Delagrange,
Bruno Pfeiffer,
Daniel-Henri Caignard,
Béatrice Guardiola-Lemaitre, and
Michel Hamon
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2081-2086
| Probes for Narcotic Receptor-Mediated Phenomena. 21. Novel Derivatives of 3-(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol-6-yl)- phenols with Improved Opioid Receptor Selectivity
Craig M. Bertha,
Matthew Ellis,
Judith L. Flippen-Anderson,
Frank Porreca,
Richard B. Rothman,
Peg Davis,
Heng Xu,
Karen Becketts, and
Kenner C. Rice
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2087-2094
| Structure-Activity Relationships of Boronic Acid Inhibitors of Dipeptidyl Peptidase IV. 1. Variation of the P2 Position of Xaa-boroPro Dipeptides
Simon J. Coutts,
Terence A. Kelly,
Roger J. Snow,
Charles A. Kennedy,
Randall W. Barton,
Julian Adams,
Dale A. Krolikowski,
Dorothy M. Freeman,
Scot J. Campbell,
John F. Ksiazek, and
William W. Bachovchin
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2095-2101
| Design and Synthesis of New Linear and Cyclic Bradykinin Antagonists
Christophe Thurieau,
Michel Félétou,
Philippe Hennig,
Eric Raimbaud,
Emmanuel Canet, and
Jean-Luc Fauchère
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2102-2102
| Synthesis of Substituted 1-Norbornylamines with Antiviral Activity
A. García Martínez,
E. Teso Vilar,
A. García Fraile,
S. de la Moya Cerero,
M. E. Rodríguez Herrero,
P. Martínez Ruiz,
L. R. Subramanian, and
A. García Gancedo
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